Sunday, November 01, 2026

Ajovy (3)

It's the first of the month and so it's time for my third Ajovy injection. As opposed to last month1, this went without difficulty, although I should note that quite a bit of force is required to remove the needle guard. This is what went wrong last time.

As to the efficacy of the injection, I can't really be sure. I've been having sleep problems for the past six weeks (difficulty in falling asleep, waking up several times during the night and difficulty returning to sleep) so I've been prescribed Brotizolam for occasional use. Although I cut each tablet into two or four, I have been using this quite frequently in the past few weeks. This makes me feel funny the next day (I have difficulty in describing the feeling, something like 'a fuzzy head' but my GP understood) and may have caused more than a few 'pressure' headaches. These feel like someone pressing on part of my head as opposed to a classic headache that hurts. It could be that rizatriptan handled these headaches, in which case they were migraines, but they could also have dissipated on their own. They certainly weren't 'normal' migraines, although these seem to come in several variations.

Regarding the sleep problems: apart from anything else, they may be due to my stopping certain medications. I have been taking Amitriptyline for years in a small prophylactic dose, and this medication can cause sleepiness - in my case, an advantage. I asked the neurologist whether I should continue taking this medication once I start with Ajovy and he said that I can stop after a month (ie at the beginning of October). The cessation could cause two separate problems: withdrawal symptoms (nothing like opiate withdrawal!!!!) and the fact that the medication's effect is simply missing.

I also stopped taking theanine once I retired as I expected that my levels of anxiety would be greatly reduced. This supplement also helps to calm the body down and improves sleep - so again, cessation might be seen as an own goal.

I had an appointment with the GP today to discuss my sleep problems, and apart from anything else, she recommended that I resume taking both of these medications as they will help with the sleep. In a few days, I'll do my biannual blood tests and next week I'll have another appointment to review the test results and any changes in the sleep. She said that there's a better medication than amitriptyline for what I need (she didn't divulge its name) and presumably next week she'll prescribe this for me.

With regard to the CPAP machine, I increased the pressure slightly as my weight has increased. It is time for a new mask that should also reduce the number of apneic events.


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This day in blog history:

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203001/11/2025More apneic eventsCPAP